I don't see how. I ran those on my KLR for years, but they're *big*, and the KLR doesn't have all the plastic... stuff.... that the VX has. Looking at mine, there's no way to get the front strap over the frame member in front of the tank (needed to keep the panniers from sliding backwards), and the plastic is angled such that they'd be pushed back into your knees. And the exhaust pipes would burn the right one, the KLR's exhaust was nicely tucked away by comparison. I'll look around in my storage bins and see if I can find my Wolfman panniers and do a test fitting, but frankly I doubt it.
2018 Versys-X 300 ABS