I had a VFR and a DRZ400S, sold both and bought a leftover 09 Versys. I had a 18" front wheel built for the DRZ...before the SM model came out. A few years ago I also had a FZ1 which didn't work out for me either.
My objectives were to reduce maintenance/insurance cost (w/one bike), improve comfort, and have a highway capable dualsport that could do 10% dirt/gravel. I really didnt like riding the DRZ on the highway, it was great up to 60 mph or so, but a bit light and buzzy (for me) at higher speeds. The VFR was too beautiful to run on dirt/gravel.
I've been real impressed w/ the Versys so far; ergonomics are very good assuming your looking for a standard riding position. Handeling is better than expected, not razor sharp like a SM but flickable and yet stable at speed. The motor/trans is plenty strong and flexible for most all types of riding, quiet and smoother than expected. It's not a torque monster at 650CC but pulls nice beyond freeway speeds and is trackable at low speed. There is even decent (and upgradable) wind management.
You didnt mention 2-up...I personally wouldnt recommend the Versys for a lot of 2-up. Also, I dont think the Versys should be confused with a FJR, GS or other high-end, large, powerful touring bike. I'm sure it can run at 80 all day, but it wouldnt be my choice, on the other hand it is a LOT more fun blasting around town and in tight canyons than larger, heavier bikes.
I stressed out about getting the 2010 vibration improvements. After riding the 09 and reading that the 10s still have a bit of vibe I'm glad I got an 09. Really, no vibes to speak of especially compared to a DRZ or even the FZ1.