Are you travelling to every state in the US? Do you have a budget? The best food I have ever eaten cost $45 a plate and doesn't fill you up. If you post your route, you might get more specific recommendations.
I am more about value when it comes to food. I know what a $1 hamburger from Wendy's tastes like. When I order a $10 hamburger I decide if it is 10 times better than a Wendy's hamburger.
Based on you liking a chain burger joint like in and out burger, which I found overpriced for what you get, I will stick with great tasting food on a budget.
Here are some of my places that I will go back to:
Hi-D-Ho in Alamogordo, NM for the Green Chili Cheeseburger. https://www.yelp.com/biz/hi-d-ho-drive-in-alamogordo
or the Rustic Café for their Green Chili Cheeseburger if you want to eat inside. https://www.yelp.com/biz/rustic-cafe-alamogordo
Rudy's BBQ in El Paso, TX for any of their smoked meats. The green chili stew is great also. They will give you samples to help you decide. https://rudysbbq.com/
Bowpicker fish and chips in Astoria, OR "Bring Cash". https://www.yelp.com/biz/bowpicker-f...hips-astoria-2
Steamboat Bill's in Lake Charles, LA the north side of I-10. Too many amazing dishes to only eat there one time. SteamBoat Bill's Restaurants
The lodge at Amicalola Falls State Park in north GA. Good food and the view is AMAZING! Amicalola Falls Amicalola Falls State Park and Lodge in Dawsonville Georgia
Just about any lobster pound in Maine for some fresh Lobsta, steamers, and lobster rolls. Every restaurant does their lobster rolls a little differently. Traditional is in a soft white hot dog bun. The one served at the Camp Store near Acadia National Park was my favorite. https://www.ottercreekinnmaine.com/market.html
If you make it over to southern Maryland, you will find yourself surrounded by ocean, Amish country, and the Chesapeake bay. Blue Crab is a must when in that area. The Ruddy Duck Brewery and Grill on St. George Island is a beautiful location to kick back and enjoy some local food. Ruddy Duck - Brewery & Grill
You can stay at the Island Inn and Suites next door so you don't have to drink and ride.
If you want more reasonably priced seafood, try Captain Pats seafood in Lexington Park, MD. Captain Pat's Seafood - Lexington Park, MD
This is all I have time for and these are the most memorable places I have eaten. I'm sure if any of the locals from those areas jump in, they may have other suggestions.