Shelter: Best, vintage, Rt. 66 style motel on the main drag (Cerrillos Road) is the El Rey (it's near my house). The Lamplighter is a good basic motel on the strip too.
Food: Get the monster breakfast burrito next door to the El Rey at The Pantry, or go downtown to Pasquals for a swankier and really good breakfast (lunch too). For dinner, try the Tune-Up Cafe on Hickox St. - nice neighborhood scene. The owner/chef is from central america, not quite mexican food, not quite new mexican food, really good. Or go to Santa Fe's best brew pub, Second Street Brewery (try the IPA), also a local scene, usually live music, always low key. The Plaza Cafe is an excellent diner with very good food, comfy, two locations including one on the historic plaza downtown.
If budget is not an issue, stay at the Inn of the Anasazi downtown for frou-frou pampering, VERY up-scale. Walk up the street to SantaCafe for a martini and quiet, white table cloth dinner.
Check the weather before you come. Last week it was cold, snowy and in the twenties, this week it's been beautiful, sunny, 70s.
If you had a day to get on the bike, you could ride over to Bandelier National Monument, mostly nice roads, great scenery. Or, day trip to Taos. Or take a short cruise out to Galisteo or to Madrid.
Around town, watch for me on the blue versys under a red helmet.