I finally gave it a shot. To me, it didn't make that much difference in a positive way. Helmet noise was maybe a little bit better, but since my commutes are mostly at freeway+ speeds, a wind break is almost a must. I have not had any buffeting issues, so removing the screen made very little difference.
I bought the bike with the Givi already on it, so I have no experience with the OEM screen and if it really makes that much difference. FWIW, I'm 6'5" and have raised the seat some and have bar risers.