Ark, I want to say the V650 will be perfect, but I am not sure given your height. I'm 5'10", and 160 pounds in full riding gear.
I find with about 10 lbs in the luggage the bike squats enough that I can flatfoot on level ground. Just barely, but I can. It took about a year for the suspension to soften up a bit, too. If you got the lower seat and the suspension lowering kit, it would probably be about the same for you. I came from bikes with lower seats, so it did take me a while to get used to the height. Also, my slow speed skills were pretty bad, which raised my anxieties about the height. Some training helped a lot with that.
The rear suspension is a bit stiff but not harsh. I keep it at the softest setting, and find I like the ride better when carrying full luggage. Usually I just keep the luggage on the bike all the time, and make no effort to pack lightly when going for a fun day ride. I found it rides and handles better with the front suspension stiffened up a bit compared to the prescribed dealer setup.
The riding position is good for my back. A cruiser position with feet out in front would be really painful for me. I can ride all day without back pain on the V.
Lifting the bike is a bit of a struggle. I've done it solo just once, and managed it ok without further wrecking my already wrecked back. I've recently had lumbar surgery for a couple of bad discs. For the past couple of years I have avoided riding solo where there wouldn't be help to pick it up if I drop it, like on isolated dirt roads.
But then again, most highway worthy bikes are going to be pretty heavy.
The 300 is a pretty interesting bike! Especially at the price. It depends on your mission, but the 300 might be a good option.